Dorsal Cluster Neurons ectopically expressing the Robo receptor - which changes the path of their axons from contralateral to ipsilateral - are highlighted by the green fluorescent protein (green). The peduncle of Mushroom Body axons is revealed by Fasiclin 2 staining (red) and the synaptic neuropil is stained by an antibody to N-Cadherin (blue).
Drosophila L3 larva eye-antennal imaginal disc.
3D rendering of contralateral dorsal cluster neuron projections stained with CD8-GFP driven with atoGal4-14a.
Photoreceptor neuron projections are highlighten by chaoptin 24B10 antibody staining (red). Green fluorescent protein (CD8-GFP) is expressed in dorsal cluster neurons using atoGal4-14a driver (green). Cell nuclei are stained with DAPI (blue).
Diversity is a beautiful thing and unity is a powerful thing. Put them together, and what do you get? You get the most beautiful and powerful of all things: evolution! Much like human beings, cells of the nervous system are exquisitely diverse. They have diverse shapes and perform diverse functions. Yet, also like humans, underneath this bewildering diversity lies a profound unity: the genome. How can exactly the same genome produce so many different cells? The answer is that it depends on how a cell interprets its genome.READ MORE